Posts Tagged ‘stem cell news’

Early Liver Creation from Human Stem Cells

Saturday, July 6th, 2013

Scientists of the Yokohama City University Graduate School of Medicine have been responsible for mixing a cocktail of induced stem cells made from adult tissue in an attempt to grow buds of human liver.

Demand for organ transplant outpaces the number of donors, with more than 118,000 Americans waiting for a life-saving transplant, according to the U.S. Department of Health and Human Services. An average of 18 people die each day waiting for an organ transplant. Stem cells, which can grow into any other type of cell, have long held the promise of bridging this gap.

“The study holds out real promise for a viable alternative approach to human organ transplants,” said Matthew Smalley, a senior lecturer at Cardiff University’s European Cancer Stem Cell Research Institute who wasn’t involved in the study.

Elizabeth Lopatto, a reporter from Bloomberg said “the buds did not function as human livers but nonetheless demonstrated what may be considered the first few steps to creating new organs for transplants”.

The entire study underwent rigorous testing where liver cells were mixed with other types of human cells, including those from umbilical cords.

Reference: http://www.bloomberg.com

Ron Received Adult Stem Cells For His Heart – He’s Back Playing Golf

Wednesday, July 3rd, 2013

As reported on www.wftv.com

About 5.8 million Americans have heart failure, a condition that occurs when the heart can no longer pump enough blood to meet the body’s needs. Now, researchers say a special type of stem cell may be the key to repairing these hearts.

Golf has always been a big part of Ron Signorelli’s life.

“I started when I was ten,” Ron told Ivanhoe.

However, Ron’s congestive heart failure was keeping him away from his favorite pastime.

“I was in the hospital over 20 times,” Ron said.

Ron’s heart pumped only 15 percent of blood. He needed help fast.

“There’s a large number of patients out there that are really in this situation where they’re gone past what normal medical therapy can do, but yet they’re not sick enough or don’t qualify for a heart transplant,” Timothy D. Henry, MD, Director of Research Minneapolis Heart Institute Foundation, told Ivanhoe.

Now, a new approach can help patients like Ron. First, doctors extract bone marrow stem cells from the patient. Then, they grow the cells to enhance their healing ability. Those cells are then injected directly into the patient’s heart.

“Our hopes are we improve the quality of their life, as well as the length of their life,” Dr. Henry said.

In the first clinical trial, the treatment was safe, repaired damaged heart muscles, and even appeared to reverse some heart failure symptoms. Ron had 12 injections and hasn’t been to the hospital since.

“I certainly feel good. I’m a very active person,” Ron said.  Now, nothing stops his stride.   See video below.

“When the weather is nice, I’ll play three, four times a week,” Ron explained.

Researchers are planning enrollment for the second phase of this trial at about 30-sites across the U.S. Once the results are assessed, the treatment will likely be more widely available. This therapy would not replace a heart transplant, but may delay or prevent the need for transplantation in the future.