Posts Tagged ‘bone marrow stem cells’

Cancer in Remission Following Stem Cell Transplant

Tuesday, October 4th, 2011

HIGH BRIDGE — Borough resident and Clinton Township Police Officer Michael Hafke and his wife Irene have transformed their 25th wedding anniversary into a celebration of life itself.

High Bridge resident and Clinton Township Police Officer Michael Hafke met his German stem cell donor, Silke Keim, for the first time during Hafke's trip to the European nation in early September. Here are donor and recipient in Keim's village of Ehringen, outside Kassel, Germany. Hafke underwent a stem cell transplant after being diagnosed with multiple myeloma, a cancer of the bone marrow.With his cancer in remission following a stem cell transplant in 2008, Hafke and his wife travelled to Germany for a vacation and to meet the person who donated the cells that saved his life.  About five years ago, Hafke was diagnosed with multiple myeloma, a cancer of the bone marrow. A donor with a close DNA match to Hafke’s could not be found in the United States, but a donor match was found in Europe.  She’s Silke Keim, a woman in her early 40s from an area in the middle of Germany called Kassel, about a two-hour drive north of Frankfurt.

 

 

 

 

 

Hafke said he would have liked to have met Keim earlier, but German law does not permit communication between a stem cell donor and recipient for at least two years.  When they met, they felt a mutual kinship.

“I’m certain we’re related,” said Hafke, who is also in his early 40s.

The Hafkes spent the first two days of their trip at the home of Keim and her husband. “They insisted that we spent the night,” Hafke said.

The German couple took the Hafkes out for dinner at a local tavern restaurant called a gasthaus. “We had schnitzel and dunkle beer,” said Hafke, describing the food and the dark German beer he had.

After the couples met again in Munich for the last two days of the trip, stem cell donor and recipient began calling each other sister and brother. Hafke said he has a strong suspicion that he and Keim may have some common ancestry, because their DNA is such a close match and since Hafke can trace his family line to a part of Germany close to the Kassel area.

Keim, however, was adopted and does not know her biological parents, so tracing her family tree may be difficult.

Before he had his stem cell transplant at Hackensack University Hospital back in 2008, Hafke had to undergo radiation treatment and a number of other procedures in preparation of receiving the cells.

Back in Germany, Keim had to undergo several procedures as well, including being connected to an apheresis machine to harvest stem cells from bone marrow cells circulating in the blood. Once the cells were collected, they had to be flown directly to the New Jersey hospital within 48 hours, Hafke said.

Saying goodbye to Keim and her family was an emotional experience, Hafke said. But the two, who literally have something quite rare in common, will meet again sometime soon, he said, either in Germany again or the United States.

By Frank Mustac  – Hunterdon County Democrat – NJ.com

Man’s Heart Saved By His Own Stem Cells

Friday, February 4th, 2011

LOS ANGELES (KABC) — For the first time in the United States, one man’s heart has been saved by his own stem cells.

It’s an amazing medical breakthrough.  The science behind the technique made it possible for a man to literally save his own life through his stem cells.

John Christy is the first person in the U.S. to have his own bone marrow stem cells injected into his heart to save his heart.

“All you’re doing is giving back to yourself something you already have,” said Christy.

This Vietnam veteran was suffering from severe coronary artery disease.

“I was just thinking, ‘You’re getting old, you’re just tiring out and getting weary bones.’ I felt tingling. My legs had been swelling a little bit,” said Christy.

In one procedure, cardiothoracic surgeon Joseph Woo at the University of Pennsylvania School of Medicine is taking science from bench to bedside. After five years of research in animals, he is now retrieving stem cells from Christy’s bone marrow and using them to grow blood vessels around the heart.

“They form brand new micro blood vessels and deliver blood flow to the heart muscle,” said Woo.

He has started the first U.S. trial where stem cells are harvested during surgery, prepped and then re-inserted back into the patient’s own heart.

Results for Christy were seen almost immediately.

“I noticed two days after my surgery, I had much more ‘umph,'” said Christy.

It’s the same process that saved 76-year-old Christina McDonald, only it wasn’t arteries in her heart that were damaged. McDonald’s problem was in her legs.

“Sort of like a charley-horse where the muscles stiffen up,” said McDonald.

The arteries in her leg were clogged with plaque, putting her at risk for heart attack, stroke and amputation. Traditionally, doctors treat it with stents, angioplasties or bypasses.  But now they’re using stem cells.

“We basically take stem cells from their hips to help grow blood vessels. It creates new, smaller blood vessels that give blood supply to the limb,” said Dr. Randall Franz, a vascular surgeon at Grant Medical Center.

It worked for McDonald.  Three months later, her pain is gone.

The same goes for Christy.  His only wish is that science was working faster.  He lost his wife to heart disease one year ago.

“I wish that she could have had this,” said Christy.

A similar procedure is being done in Europe. The difference is Woo does his in one short surgery.

In Europe, it takes at least two procedures, weeks apart.

Woo says any patient who is a candidate for coronary bypass surgery is a good candidate for his stem-cell transplant.

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