Posts Tagged ‘adult stem cells’

Man’s Heart Saved By His Own Stem Cells

Friday, February 4th, 2011

LOS ANGELES (KABC) — For the first time in the United States, one man’s heart has been saved by his own stem cells.

It’s an amazing medical breakthrough.  The science behind the technique made it possible for a man to literally save his own life through his stem cells.

John Christy is the first person in the U.S. to have his own bone marrow stem cells injected into his heart to save his heart.

“All you’re doing is giving back to yourself something you already have,” said Christy.

This Vietnam veteran was suffering from severe coronary artery disease.

“I was just thinking, ‘You’re getting old, you’re just tiring out and getting weary bones.’ I felt tingling. My legs had been swelling a little bit,” said Christy.

In one procedure, cardiothoracic surgeon Joseph Woo at the University of Pennsylvania School of Medicine is taking science from bench to bedside. After five years of research in animals, he is now retrieving stem cells from Christy’s bone marrow and using them to grow blood vessels around the heart.

“They form brand new micro blood vessels and deliver blood flow to the heart muscle,” said Woo.

He has started the first U.S. trial where stem cells are harvested during surgery, prepped and then re-inserted back into the patient’s own heart.

Results for Christy were seen almost immediately.

“I noticed two days after my surgery, I had much more ‘umph,'” said Christy.

It’s the same process that saved 76-year-old Christina McDonald, only it wasn’t arteries in her heart that were damaged. McDonald’s problem was in her legs.

“Sort of like a charley-horse where the muscles stiffen up,” said McDonald.

The arteries in her leg were clogged with plaque, putting her at risk for heart attack, stroke and amputation. Traditionally, doctors treat it with stents, angioplasties or bypasses.  But now they’re using stem cells.

“We basically take stem cells from their hips to help grow blood vessels. It creates new, smaller blood vessels that give blood supply to the limb,” said Dr. Randall Franz, a vascular surgeon at Grant Medical Center.

It worked for McDonald.  Three months later, her pain is gone.

The same goes for Christy.  His only wish is that science was working faster.  He lost his wife to heart disease one year ago.

“I wish that she could have had this,” said Christy.

A similar procedure is being done in Europe. The difference is Woo does his in one short surgery.

In Europe, it takes at least two procedures, weeks apart.

Woo says any patient who is a candidate for coronary bypass surgery is a good candidate for his stem-cell transplant.

(Copyright ©2011 KABC-TV/DT. All Rights Reserved.)

Stem Cell Spray Heals Burns

Sunday, November 28th, 2010

 

 
Stem Cell Spray Heals Burns 
 
November 26th, 2010 @ 11:25pm
By Ed Yeates.    Video Courtesy of KSL.com

SALT LAKE CITY — A spray solution of a patient’s own stem cells is healing their severe burns. So far, early experiments under a University of Utah pilot project are showing some remarkable results.

What was once a serious burn on Kaye Adkins foot is healing nicely now because of a topical spray. With diabetes as a complication, the small but open wound had not healed after weeks of failed treatments.

Dr. Amalia Cochran with the university’s Burn Care Center says, “With a wound that is open for several months, as this patient suffered prior to seeing us in our burn clinic, we worry about a pretty heavy bacterial load there.”

But enter the evolutionary world of regenerative medicine, using almost a bedside stem cell technique that takes only about 15 minutes. With red cells removed, a concentrate of platelets and progenitor cells is combined with calcium and thrombin. The final mixture looks almost like Jello.

“I woke up and saw them with this big thin, looked like a needle, and I said you’re going to put that in my foot? And they said NO, we’re going to spray,” Adkins said.

Though her own skin graft had failed before, the topical spray was used during a second graft. It “took” and healed. “I had never heard of anything like that. It was just amazing,” Adkins said.

Adkins burn is healing and so is her heart. Coincidentally, stem cells were used during her bypass surgery five weeks ago to hasten healing for that procedure as well. While hundreds of heart patients have had stem cell treatments, burn patients are still few in numbers.

Cardiothoracic surgeon Amit Patel and burn care surgeon Amalia Cochran are experimenting on small burns for now. But down the road, both are hoping for large scale clinical trials on patients with much larger burns.

Patel asks, “Can we accelerate healing or improve healing. Then it’s the quality of healing. And then, we hopefully advance to decreasing the scarring process completely.”

“It’s my hope that in my career,” Cochran adds, “stem cells will completely revolutionize how we’re able to take care of patients. Not just with small burns that are challenging to heal, but with massive burn injuries as well.”

The military is keeping a close eye on the Utah project. The future for treating burns on soldiers could stagger the imagination even more. Patel says “regrowing your own skin in a bioreactor is very realistic and that’s not five years away even. We start with a biological band aid and hope to end up with basically synthetic skin that’s still derived from your own cells.”

In this dream of regenerative medicine, Patel believes we can only imagine a day when sheets of pristine skin might be available to any patient off the shelf.