Two cancer patients in Boston who were also infected with Human Immunodeficiency Virus (HIV) have no trace of the virus after receiving stem-cell transplants, suggesting they may have been cured of the Acquired Immuno Deficiency Syndrome(AIDS) causing infection.
The two patients, treated at Brigham and Women’s Hospital in Boston, stopped HIV treatment after the transplants, which in other patients has opened the door for the virus to come roaring back. In one patient there was no sign of the virus 15 weeks after stopping treatment, while the other has gone seven weeks without HIV rebounding, according to results presented today at the International AIDS Society’s meeting in Kuala Lumpur.
The researchers led by Timothy Henrich of Harvard Medical School and Brigham and Women’s Hospital said it’s too early to conclude the two men have been cured and the virus may be lingering in their brains or gut. Still, their cases are similar to that of Timothy Brown, the so-called Berlin patient, who was the first person to be cured of HIV after getting a bone marrow transplant for leukemia in 2007.
While stem-cell transplantation is not a viable option for people with HIV on a broad scale because of its costs and complexity, these new cases could lead us to new approaches to treating, and ultimately even eradicating, HIV, Kevin Robert Frost, the chief executive officer of amfAR, The Foundation for AIDS Research, which funded the study, said in a statement.
Researcher Timothy Henrich
Read more at: http://www.livemint.com
