StemCellWorx Articles

Stem Cell Injection To Help Arm Movement After Stroke

November 22nd, 2015

Stem Cell Injection

Source: http://home.bt.com/

A 66-year-old woman has become the first in England to undergo a stem cell brain injection to help recover the use of her arm after she suffered a stroke.

Diederik Bulters, a consultant neurosurgeon at Southampton General Hospital, and his team – which consisted of 17 colleagues – carried out the procedure after the woman lost functional movement in her arm when she suffered a stroke a year ago.

The treatment, which will be trialled on 41 patients as part of a UK-wide study known as Pisces II, works by delivering stem cells into the part of the brain that is believed to help generate new nerve cells.

The technique was first used in 2010 at Glasgow’s Southern General Hospital for an early-stage study, which involved a total of 11 patients aged in their 60s, 70s and 80s, which found it was safe and preliminary findings showed promising results.

Every year, around 110,000 people in England suffer a stroke and it is the third largest cause of death behind heart disease and cancer.

A hospital spokesman said: “The majority of strokes are caused by a blockage of blood flow in the brain, known as ischaemic stroke, and around half of all survivors are left with permanent disabilities, with the most common being paralysis of the face, arm and leg on one side of the body.

“After initial treatment for a stroke, which involves having clot-busting drugs administered within several hours of the onset of the condition, there are no existing treatments, other than ongoing rehabilitation, to alleviate the disabilities caused as a result.”

Mr Bulters said: “This is a really exciting study and we are delighted to be a part of it and be able to offer some of our patients the opportunity to trial this potentially revolutionary treatment.

“The treatment was tested successfully in a small, early-stage study in Scotland, which showed the technique to be safe, so what we need to do now is quantify how much benefit is derived from it.”

He added: “While we have made great strides in this country in treating the onset of a stroke, there is little that can currently be done to improve the lives of so many survivors who are left permanently disabled as a result – but this project could change that.”

A second patient, a 72-year-old woman, has now received the injection at Southampton General Hospital and the study is under way at 11 other units in the UK.

 

Baby Girl With Crohn’s Disease Returns Home After Successful Stem Cell Treatment

November 13th, 2015

Chron's Disease Transplant for BabySource:  ShanghaiDaily.com

A BABY girl was discharged from hospital yesterday after undergoing stem cell therapy to treat a bowel disease that likely killed her sister, doctors told Shanghai Daily.

Zhao Jiaxin, now 10 months old, is the first person in China to be treated for Crohn’s disease using stem cells from donated umbilical cord blood.

When she was just 8 days old, Zhao began suffering from diarrhea and fever — symptoms that had beset her sister, who died when she was 5 months old.

“We feared so much that we might lose her, too,” Ji Jiannan, the baby’s mother (pictured above), said after her daughter was discharged from hospital yesterday.

Zhao’s father, Zhao Mingwei, said: “Our first daughter succumbed to the disease, so when Yuanyuan (Zhao’s nickname) started showing the same symptoms when she was just a week old, we were terrified.”

“We took her to several local clinics, but nothing worked,” he said.

The family lives in central China’s Henan Province, but, after finding no luck at home, they decided to take the baby to Shanghai in March.

It was there, at Fudan University’s Children’s Hospital that the infant underwent the life-saving procedure.

After hearing the story of Zhao’s sister, doctors conducted a series of genetic tests on the baby and determined she was suffering from Crohn’s disease.

“The only effective treatment is a stem cell transplant,” Dr Huang Ying, director of the hospital’s digestive disease department, told Shanghai Daily.

“It can help to repair the genetic deformity and control the symptoms of the disease,” he said.

Zhao’s stem cells were NOT controversial as they were extracted from the blood of a donor’s umbilical cord.

In the past, bone marrow has been used in similar procedures. On average, recovery takes about six months.

“The baby’s condition improved rapidly once she had received the umbilical cord cell transplant. She was discharged last night and returned home to Henan Province with her parents,” Huang said.

Mom Ji couldn’t have been happier.

“I remember when she was 100 days old, she was skinny like a skeleton. Now look at her: She’s almost got a puffy face,” she said.

With the help of social workers, the family managed to raise 300,000 yuan (US$47,000) to cover the therapy fees.

“I just think my family is really lucky,” she said.

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