Archive for the ‘adult stem cell activation’ Category

Lung Disease Sufferers Explore Stem Cell Therapies as Alternative to Lung Transplant

Tuesday, November 5th, 2013

New Lungs

Regenerative medicine is the latest medical technology for the restoration and repair of damaged lung tissue caused by lung disease. As the leaders in lung treatment, Lung Institute’s physicians have harnessed this advancement in modern medicine to bring patients suffering with conditions like chronic obstructive pulmonary disease (COPD), emphysema, chronic bronchitis, and pulmonary fibrosis an innovative treatment choice that betters their quality of life and helps them to breathe easier.

Often, many of these patients have been told that lung transplantation is their only option, and as a result many are turning to advanced treatments such as pulmonary stem cell therapies to enhance lung function and regenerate healthy lung tissue.

Stem Cell Therapy vs. Lung Transplant for Lung Disease

Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and mortality in the United States, and a top five cause of death worldwide. Although there are many suppressive treatments available to COPD sufferers, the progressive nature of this disease almost unavoidably leads to a diminished quality of life.

Often, once most types of conventional treatment methods are exhausted, COPD sufferers are told that their treatment path is going to result in a lung transplant. Before undergoing this invasive, and sometimes risky, surgery it is important to know the outcomes of a lung transplant.

The excerpt below, from the National Institutes of Health (NIH), outlines the life expectancy of an individual post lung transplant surgery.

“In recent years, short-term survival after lung transplant has improved. Recent data on single-lung transplants show that:

  •     About 78 percent of patients survive the first year
  •     About 63 percent of patients survive 3 years
  •     About 51 percent of patients survive 5 years

Survival rates for double-lung transplants are slightly better. Recent data shows that the median survival for single-lung recipients is 4.6 years. The median survival for double-lung recipients is 6.6 years.

As you can see, the median number of years added to a person’s life post lung transplant ranges from 4.6 years to 6.6 years depending on the type of surgery received. This procedure can improve quality of life, but there is also risk of complications including infection, rejection of the new lung(s), and in some cases, an increased chance of developing diabetes, kidney damage, and osteoporosis.

Regenerative therapies are emerging as an alternative and preemptive treatment, to the invasive option of lung transplantation.

How do stem cells restore damaged lung tissue?

Lung Institute utilizes autologous stem cells, meaning those derived from the patient’s own blood or fat tissue, for treatment. These somatic, or adult stem cells have the unique ability to self-renew and replicate, and are capable of forming any type of tissue found in the human body, including lung tissue.

What is the stem cell treatment process like?

This minimally invasive, outpatient procedure is performed over the course of three days within the Lung Institute’s Office located in downtown Tampa, FL. For pulmonary conditions, the stem cells are stimulated to increase in number by oral and injectable agents. Next, the stem cells are derived from the patient’s own blood or bone marrow and are given back to the patient intravenously.

In conclusion: Stem Cell Therapy vs. Lung Transplant for Lung Disease

Both stem cell therapies and lung transplantation have been proven, in many cases, to improve sufferer’s quality of life. However, lung transplantation is an invasive, inpatient surgery that can have risky complications and a longer recovery time.

Stem cell therapies do not replace the need for a lung transplant, but can slow the progression of lung disease, and therefore prolong the need for a transplant. Stem cells and other forms of regenerative therapies are also proven to significantly improve sufferer’s quality of life.

A recent Lung Institute patient, Peter Pike, was diagnosed with COPD and underwent stem cell therapies with at our clinic in Tampa a little over 5 months ago. He is now able to perform everyday functions without feeling out of breath; even his wife says his overall disposition has improved. To learn more about how Pike’s life has improved, watch his testimonial video by clicking here.

Reference: http://www.digitaljournal.com/pr/1560123

Radical Stem Cell Transplant for Acute Renal Failure

Saturday, October 12th, 2013

AUSTRALIAN rock legend Jim Keays has narrowly survived acute renal failure after a radical stem cell transplant he hopes will save his life.

Jim Keays and Russell Morris for Blog

Keays was diagnosed with multiple myeloma – a cancer of the blood’s plasma cells – six years ago and has been battling the disease since.

Myeloma often attacks the kidneys and Keays had chemotherapy and was put on dialysis after seeing his kidney function drop to 5 per cent.

Early this year he had a transplant using stem cells harvested from his own blood.

Then in radical, and still experimental, surgery, he recently received stem cells from an unknown donor – a man who does not even share Keays’ blood group.

“There is a global register of stem cells donors, and the doctors told me they had found a reasonable match on it,” the former Master’s Apprentices’ frontman explained.

All Keays, who turned 67 last month, knows of the donor is that he is 28 years old and from New Jersey.

When doctors explained the treatment Keays was told it was his “last roll of the dice”.

“The alternative was to die,” said Keays.

The Alfred flew a staff member to America to pick up the donated stem cells while Keays was given radiation therapy to subdue his body’s natural defence against foreign tissue.

“They operated on me nine weeks ago after zapping my immune system,” he said. “It allowed (the donor) stem cells to come in unchallenged.”

It seemed to go well but, as Keays was warned it might, graft-versus-host disease developed – a regular complication from such procedures.

“They warned me that it was still experimental and that there would be drawbacks.”

Not only is the donor not Keays’ blood type, the singer will now “inherit” the donor’s blood group and immune system.

Doctors have kept Keays alive in a complex balancing act involving a mix of sometimes debilitating medications.

“They tweak it on a daily basis,” he explained.

Keays’ kidneys failed in August and he had to call his daughter along with his musical offsider, Russell Morris, to carry him out of the house and on to hospital.

“It’s the third time I’ve been close to death, but now they say I am tracking really well,” he said.

“The donor cells appears to have imbedded themselves properly. I should be virtually free of the cancer.”

Keays has been a fixture on the Australian music scene for more than 45 years after bursting out of Adelaide with the Masters in 1966.

The band’s hits included Undecided, Elevator Driver, 5.10 Man, Turn Up Your Radio and Because I Love You.

For 12 years he performed as part of Cotton Keays Morris until cancer claimed Darryl Cotton last year.

Myeloma is incurable, but Keays has been told it is now almost undetectable and that he no longer requires medication.

He is deeply indebted to the specialists at The Alfred Hospital who are among the foremost experts in his disease in the world. And Keays wants to encourage more blood donations. “Give blood, donate stem cells, be an organ donor,” he said.

Keays, who hasn’t worked in nine months, is looking at hooking up with Morris for some performances later in the year.

“Russell has waited for me. I’ll be able to live a normal life again.

“There’s a tunnel. But I’ve spotted a light.”

Source:       
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