Archive for May, 2014

A Must Read Before You Buy Health Supplements

Tuesday, May 13th, 2014

Spray Then Go_Stem Cell Worx

Don’t waste your hard earned cash on the wrong type of health supplements. Here are 5 key points to consider before you buy any health supplement.

1.   Absorption is Everything

A health supplement in liquid form that is consumed by spraying under the tongue is known as intraoral delivery.

In certain contexts, it may be referred to as sublingual.  Intraoral is a viable way to take your health supplements as it offers an absorption rate of up to 95% of its nutrients compared to only a 10% to 20% absorption rate that pills and capsules provide. The sub-mucosal membrane that sits under our tongue enables nutrients taken intraorally to get directly into the bloodstream, straight away. You are therefore not wasting 80% to 90% of the nutrients as you do with pills and capsules.

Intraoral (apart from intravenous) provides the most concentrated source of nutrient delivery. See the graph below that illustrates absorption rate percentages for various applications.

Many pills and capsules when taken orally are quickly digested and metabolized in the intestines and liver, resulting in less than 5 percent of the oral dose in pill and capsule form remaining in the blood plasma. This metabolic process is known as the “first pass effect,” and results in the compounds being eliminated from the digestive and urinary system right after ingestion. Even if larger dosages of ingredients are consumed in pill form or a certain type of capsule coating is used (i.e. vegetable capsule), in almost all cases its concentration levels inside the blood still fail to reach the required levels necessary for effective nutritional value and most ingredients within the pill don’t even reach required levels for laboratory testing conditions. Intraoral delivery avoids the “first pass effect” issue.

Absorption Rates_Stem Cell Worx Blog

This study found resveratrol administered by intraoral delivery is 250 times more effective than when taken in pill form.

2.   Always Check The Label

Have you ever come across a health supplement that states the ingredients only in IUs (International Units) or Mcgs (micrograms)?   Like nanograms (ngs) these measurements can equate to zilch. It is crucial you understand what these measurements equate too before you buy your health supplements.

Example 1.    Converting IUs into Mgs

1a)          1 mcg Vitamin D3 (cholecalciferol) = 40 IU. Don’t mistake mcgs for mgs.

They are totally different measurements, and many people often don’t see the small “c” within mcgs, especially as supplement facts are often displayed in small text on the label.

1b)         Let´s say you have 300 IU of Vitamin D: 300 / 40 = 7.5 mcg Vitamin D.

Then you would have to convert 7.5 mcg to mg: 7.5 / 1000 = 0.0075mg Vitamin D (less than 1mg).

1c)          Another example, 5000 IUs of Vitamin D becomes 0.125mg of Vitamin D.

Example 2.    Ng, MCG, MG and G Conversation Rates

5000mcg = 5mg

1000 nanograms (ng) = 1 microgram (mcg)

1000 micrograms (mcg) = 1 milligram (mg)

1000 milligrams (mg) = 1 gram (g)

It is recommended you buy health supplements that state the ingredients in milligrams (mgs) or grams.   If IUs, Mcgs or Ngs are noted, ensure you do the math. Here are a couple of conversion tables to help you.

http://www.thecalculatorsite.com/conversions/common/mcg-to-mg.php

http://www.etoolsage.com/converter/IU_Converter.asp

3.   Beware of Proprietary Blends

When a proprietary blend of ingredients is shown on the supplement label and no percentages of purity shown for each ingredient, this generally means a number of poor, low grade ingredients have been mixed together with practically no purity or nutritional value whatsoever.

Always look for standalone ingredients to be noted separately on a supplement label with the percentage of purity noted against each ingredient.

4.   Beware of Certain Fillers, Binders and Artificial Sweeteners

Fillers, binders and artificial sweeteners will generally be noted under the “other” section at the bottom of the supplement fact panel.  Sometimes they are noted as “inactive” ingredients. Most of these substances are not good for you. They are mostly used to bind ingredients together, fill and/or lubricate capsules, pills and tablets and are often used only to aid consumption and/or accelerate manufacturing processes.

Fillers and binders are not so common in liquid supplements because they are not required, as per the points below. Binders are mostly used to bind or hold ingredients together.  They are typically a sugar derivative and include: lactose, sucrose, microcrystalline cellulose, sorbitol, propylene glycol, xylitol to name a few.

Sweeteners such as corn, sucralose (or splenda) should be avoided.  In 2013 Splenda (sucralose) was downgraded from “safe” to “caution” after an Italian animal study linked sucralose to a higher risk of developing leukemia.

Magnesium stearate is used as a lubricant. It is formed by adding a magnesium ion to stearic acid. It is mostly used in vitamins to avoid them sticking to one another or the equipment when they are manufactured.  Research to date shows the stearic acid suppresses T cells (your natural killer cells) that are a key component of a healthy immune system. Avoid hydrogenated oils.  These have been found to encourage heart problems and upset blood sugar regulation.

The bottom line is you don’t want fillers, binders and artificial sweeteners in your health supplements.

5.   Intraoral Spray Supplements Provide Huge Advantages

Whenever possible buy your quality health supplements in liquid form (preferably for administration via intraoral spray or in dropper form).

Remember to still check the points above. A wide range of quality liquid health supplements are now available.

Until now, buccal and intraoral spray delivery had been best advised for smaller particle molecules, therefore most vitamins and minerals ideally suit this form of administration. However, more recent science shows a great deal of biological compounds, nutraceuticals and drugs can be effectively administered in intraoral format.  This is also a much more cost effective method of administration as a lower dosage of ingredient is required due to this being such a concentrated source of delivery.

The intraoral route of administration has recently been investigated for insulin and heparin. [Reference:  International Journal of Pharmacy and Pharmaceutical Science Research – ISSN: 2249-0337 – February 2013 and Life Enhancement Magazine].

Key Advantages of intraoral delivery

  • Increased bioavailability
  • Higher plasma levels
  • Rapid absorption and onset of actions
  • Avoids pre-systemic elimination in the GI tract
  • Avoids first-pass effect of the liver
  • Avoids exposure to a hostile GI environment
  • Ability to swallow is not required

From the Stem Cell Worx Team

Excellence in Nutritional Supplementation

 

(Copyright ©2014-2015 Stem Cell Worx. All Rights Reserved.)

 

Daughter Provides Stem Cells To Give Mom Better Vision

Sunday, May 11th, 2014

Click link below to view video:

http://launch.newsinc.com/share.html?trackingGroup=69016&siteSection=suntimes&videoId=25983503

Debra Astrug was struggling. She couldn’t read or drive, she worried about crossing the street to get the mail, and she couldn’t draw.

“I’m an artist, and I couldn’t draw. I couldn’t at all,” said the 57-year old Elgin woman, whose vision had been deteriorating for six years, becoming blurry as the result of graft versus host disease, which was a side effect of a successful bone marrow transplant from her sister in 1996 to treat cancer.

“It’s like I was going blind. Basically everything was becoming just shapes rather than defined. I couldn’t see anything clearly,” Astrug said. “Even baking something . . . my daughter had to put on my stove “On” and “Off” with huge print so I would be able to see it.”

Astrug needed another transplant, this time of corneal stem cells from a living donor to fix her limbal stem cell deficiency, which causes the cornea to be covered with abnormal tissue. She underwent the transplant in March 2013 at Loyola University Medical Center in Maywood, Illinois, United States of America and now has near-perfect vision with a therapeutic lens.

Astrug’s sister would have been an ideal candidate to donate the tissue, but she died in 2005 from stomach cancer. Next best would be her three adult children, Jessica, Lauren and Peter Astrug, all of whom were willing to donate to their mother, a widow.

Jessica, 31 and the oldest, lives closest to her mother in Pingree Grove and would drive her where she needed to go. Logistically, it made the most sense for her to donate the two pieces of tissue needed to correct her mother’s eyesight.

“She’s always been there for me. She has gone through a lot in her life,” Jessica said. “My mom would do anything for me, and I’d do anything for my mom.”

Dr. Charles Bouchard, who performed the surgery, removed two small pieces of tissue from Jessica’s right eye, and then went into the other operating room where he harvested additional stem cells from an eye bank cornea donor and then went to work on Debra.

“We then removed the abnormal tissue from Debra’s cornea and, using biological glue, attached the stem cells from Jessica as well as those from the eye bank cornea,” Bouchard said, noting that the procedure is uncommon but several corneal surgeons in Chicago perform such stem cell transplants.

There was no guarantee the procedure would work, but Debra Astrug’s vision improved to 20/25 within several months, he said. Her vision before the procedure was 20/100 to 20/200.

Jessica healed quickly. She returned to work after a week and got her stitches out after two weeks.

“The biggest discomfort was the stitches in my eye,” Jessica said. “It was very uncomfortable. It felt like I had an eyelash or a grain of sand in my eye, but I couldn’t touch it because I risked pulling one of the sutures out.”

Bouchard said the biggest risk for Jessica is the chance of developing stem cell deficiency in the future, but that would be rare.

The stem cell transplant restores the normal outer layer of the cornea, which is the clear part of the eye. “If there is scarring or other causes of vision loss, like macular degeneration, or glaucoma or optic nerve disease, this procedure will not help blindness from these causes,” Bouchard said.

Watching her mother return to normalcy is “fantastic,” Jessica said.

“I drove her everywhere all the time, so now to see her in the car on her own, driving, driving at night, and she’s fine — it’s amazing.”
Debra Astrug agrees, even though no one knows how long the surgery results will last.

“I’ve had a lot of improvement in the past year. I can wear the [therapeutic] lens all day, and my vision is good,” she said. “It’s not always 100 percent; it goes in and out during the day and gets blurred sometimes. If I go into building where air is forced, my eyes dry out and can’t see as well. That will always be a problem, but I’ll deal with it. I have my general eyesight back, and that’s more than I ever hoped for.”

On Sunday, May 11th 2014, Astrug says, her daughter plans to take her to dinner to celebrate Mother’s Day.

“It brings a family closer when things like this happen,” Astrug said. “It doesn’t matter that it’s Mother’s Day. We love each other all the time.”

Source:  Chicago Sun-Times